| Primary Identifier | MGI:2137648 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 65972 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable oxidoreductase activity, acting on a sulfur group of donors. Involved in antigen processing and presentation of exogenous peptide antigen via MHC class I. Acts upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II; negative regulation of fibroblast proliferation; and protein stabilization. Located in lysosome. Is expressed in gut; liver; orbito-sphenoid; and submandibular gland primordium. Orthologous to human IFI30 (IFI30 lysosomal thiol reductase). PHENOTYPE: No phenotypic abormalities have been reported in mice homozygous for disruptions in this gene other than reduced efficiency in processing some antigens. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
