Primary Identifier | MGI:2443304 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 270058 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables actin filament binding activity; identical protein binding activity; and microtubule binding activity. Involved in brain development. Acts upstream of or within microtubule cytoskeleton organization. Located in dendrite; microtubule cytoskeleton; and neuronal cell body. Is expressed in brain and spinal cord. Orthologous to human MAP1S (microtubule associated protein 1S). PHENOTYPE: Mice homozygous for a knock-out allele exhibit defective biogenesis and degradation of autophagosomes. [provided by MGI curators] |