| Primary Identifier | MGI:1916800 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 69550 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metalloendopeptidase inhibitor activity and protein homodimerization activity. Involved in several processes, including negative regulation of intracellular transport of viral material; negative regulation of viral genome replication; and response to type II interferon. Located in cell surface. Is expressed in cerebral cortex and retina. Human ortholog(s) of this gene implicated in acquired immunodeficiency syndrome and endometrial cancer. Orthologous to human BST2 (bone marrow stromal cell antigen 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased susceptibility to the LP-BM5 strain of Mo-MLV (murine AIDS). [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
