| Primary Identifier | MGI:1347098 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 26457 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables several functions, including fatty acid-CoA ligase activity; identical protein binding activity; and protein serine/threonine kinase activator activity. Involved in glucose import in response to insulin stimulus; long-chain fatty acid import into cell; and positive regulation of triglyceride biosynthetic process. Acts upstream of or within several processes, including adiponectin-activated signaling pathway; fatty acid transport; and response to insulin. Located in basal plasma membrane and endoplasmic reticulum. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; phalanx; and sensory organ. Orthologous to human SLC27A1 (solute carrier family 27 member 1). PHENOTYPE: Homozygous null mutants are protected from fat-induced insulin resistance and intramuscular accumulation of fatty acid metabolites without alterations in whole body adiposity. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
