Primary Identifier | MGI:1919304 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 72054 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables long-chain fatty acid omega-1 hydroxylase activity. Involved in leukotriene B4 metabolic process. Predicted to be located in apical plasma membrane; cytoplasm; and intracellular membrane-bounded organelle. Orthologous to several human genes including CYP4F3 (cytochrome P450 family 4 subfamily F member 3). PHENOTYPE: Mice homozygous for a knock-out allele exhibit altered leukotriene B4 metabolism but show no significant alterations in inflammatory cell infiltration or injury following renal ischemia-reperfusion. [provided by MGI curators] |