| Primary Identifier | MGI:1342772 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 16598 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity. Acts upstream of or within several processes, including erythrocyte maturation; regulation of gene expression; and type I pneumocyte differentiation. Located in nucleus. Is expressed in several structures, including heart; limb mesenchyme; sensory organ; skeleton; and tooth. Orthologous to human KLF2 (KLF transcription factor 2). PHENOTYPE: Mice homozygous for targeted null mutations die during organogenesis with growth retardation, massive hemorrhage, and signs of anemia. Mice homozygous for one allele also display craniofacial malformations and impaired hematopoiesis. A second allele causes vascular abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
