Primary Identifier | MGI:1925764 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 78514 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTPase activator activity. Involved in negative regulation of apoptotic process. Acts upstream of or within cytoskeleton organization. Located in cytosol. Is expressed in brain. Orthologous to human ARHGAP10 (Rho GTPase activating protein 10). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit paraparesis, ataxic hindlimbs and splaying of hindlimbs. [provided by MGI curators] |