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Protein Coding Gene : Smarca5 SNF2 related chromatin remodeling ATPase 5

Primary Identifier  MGI:1935129 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  93762
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable several functions, including ATP binding activity; ATP hydrolysis activity; and nucleosome array spacer activity. Predicted to contribute to histone binding activity. Involved in negative regulation of macromolecule biosynthetic process and positive regulation of DNA replication. Acts upstream of or within cellular response to leukemia inhibitory factor; chromatin organization; and positive regulation of DNA-templated transcription. Located in nucleus and pericentric heterochromatin. Part of CERF complex; NoRC complex; and chromatin silencing complex. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human SMARCA5 (SNF2 related chromatin remodeling ATPase 5).
PHENOTYPE: Homozygous mutant mice die during early embryonic development. [provided by MGI curators]
  • synonyms:
  • SNF2 related chromatin remodeling ATPase 5,
  • MGI:2443329,
  • RIKEN cDNA 4933427E24 gene,
  • Smarca5,
  • RIKEN cDNA D330027N15 gene,
  • MGI:1918447,
  • 4933427E24Rik,
  • D330027N15Rik,
  • Snf2h,
  • modifier of murine metastable epialleles, D4,
  • D030040M08Rik,
  • MGI:2441934,
  • MommeD4,
  • RIKEN cDNA D030040M08 gene,
  • MGI:3586540

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

12 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For