| Primary Identifier | MGI:1922091 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 74841 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cysteine-type deubiquitinase activity and protein sequestering activity. Predicted to be involved in negative regulation of innate immune response; negative regulation of proteasomal ubiquitin-dependent protein catabolic process; and regulation of protein stability. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human USP38 (ubiquitin specific peptidase 38). PHENOTYPE: Mice homozygous for a null allele exhibit increased susceptibility to bleomycin-induced inflammation, fibrosis, and lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
