| Primary Identifier | MGI:2142433 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 666704 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables low-density lipoprotein particle binding activity. Involved in foam cell differentiation; lipoprotein lipid oxidation; and negative regulation of transcription by RNA polymerase II. Is active in extracellular space. Is expressed in several structures, including alimentary system; extraembryonic component; hemolymphoid system gland; umbilical artery; and umbilical vein. Orthologous to human SAMD1 (sterile alpha motif domain containing 1). PHENOTYPE: Mice homozygous for a null allele die during fetal development with failure of blood vessels to mature, exencephaly, pallor, and degradation of organs. Mice heterozygous for the allele exhibit failure to thrive and altered steroidogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
