| Primary Identifier | MGI:2675387 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 244551 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables RNA binding activity. Involved in regulation of cell cycle; regulation of translation; and spermatogenesis. Acts upstream of or within negative regulation of apoptotic signaling pathway and oogenesis. Located in P-body; cytoplasmic stress granule; and nucleus. Is expressed in several structures, including gonad; metanephros; primordial germ cell; and telencephalon. Orthologous to human NANOS3 (nanos C2HC-type zinc finger 3). PHENOTYPE: Homozygous inactivation of this locus results in both male and female infertility. Both male and female gonads are reduced in size and are devoid of germ cells, putatively due to impaired maintainence of primordial germ cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
