| Primary Identifier | MGI:1928379 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 56495 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable ATP hydrolysis activity and membrane insertase activity. Predicted to be involved in tail-anchored membrane protein insertion into ER membrane. Predicted to act upstream of or within post-translational protein targeting to endoplasmic reticulum membrane. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of GET complex. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including central nervous system; foregut; ganglia; respiratory system; and tooth. Human ortholog(s) of this gene implicated in dilated cardiomyopathy. Orthologous to human GET3 (guided entry of tail-anchored proteins factor 3, ATPase). PHENOTYPE: Mice homozygous for a null mutation display early embryonic lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
