Primary Identifier | MGI:2683592 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 330817 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables deoxyhypusine synthase activity. Involved in peptidyl-lysine modification to peptidyl-hypusine. Acts upstream of or within glucose homeostasis and positive regulation of T cell proliferation. Is active in cytosol. Orthologous to human DHPS (deoxyhypusine synthase). PHENOTYPE: Mice homozygous for a knock-out or gene trap allele exhibit embryonic lethality prior somite formation. [provided by MGI curators] |