| Primary Identifier | MGI:1915086 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 67836 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Acts upstream of or within several processes, including neural tube closure; placenta blood vessel development; and regulation of canonical NF-kappaB signal transduction. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; decidua; extraembryonic component; islets of Langerhans; and renal proximal tubule. Orthologous to human WDR83 (WD repeat domain 83). PHENOTYPE: Mice homozygous for a reporter allele exhibit embryonic lethality at E10.5 due to diffuse vascularization and placental insufficiency. Mice heterozygous for the same reporter allele exhibit decreased susceptibility to kidney reperfusion injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
