| Primary Identifier | MGI:1929285 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 56452 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA binding activity. Acts upstream of or within DNA-templated DNA replication. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be part of nuclear origin of replication recognition complex. Is expressed in several structures, including brain ventricular layer; early conceptus; jaw; liver lobe; and submandibular gland primordium. Human ortholog(s) of this gene implicated in Meier-Gorlin syndrome 3. Orthologous to human ORC6 (origin recognition complex subunit 6). PHENOTYPE: Mice homozygous for a knock-out allele show complete embryonic lethality before implantation associated with abnormal morula morphology, increased cell death, and failure of blastocyst formation. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
