Primary Identifier | MGI:1306779 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 20299 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable CCR chemokine receptor binding activity and chemokine activity. Predicted to be involved in several processes, including antimicrobial humoral immune response mediated by antimicrobial peptide; chemokine-mediated signaling pathway; and eosinophil chemotaxis. Located in extracellular space. Is expressed in dermis; epidermis; inguinal lymph node; thymus; and thymus primordium. Orthologous to human CCL22 (C-C motif chemokine ligand 22). PHENOTYPE: Mice homozygous for a knock out allele exhibit dendritic cell physiology relating to CCR4-mediated cell contacts between dendritic cells and cytotoxic T cells. [provided by MGI curators] |