| Primary Identifier | MGI:107434 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 12564 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables identical protein binding activity. Involved in regulation of synapse organization. Acts upstream of or within glutamatergic synaptic transmission and response to cold. Located in axon terminus and synaptic cleft. Is active in glutamatergic synapse and synaptic membrane. Is expressed in several structures, including alimentary system; cardiovascular system; nervous system; respiratory system; and sensory organ. Orthologous to human CDH8 (cadherin 8). PHENOTYPE: Mice homozygous for a null allele are viable, fertile and overtly normal but display abnormal CNS synaptic transmission, raise their tails in response to stress, and show reduced sensitivity to cutaneous cold stimuli. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
