Primary Identifier | MGI:99217 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 12552 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable beta-catenin binding activity and cadherin binding activity. Involved in modulation of chemical synaptic transmission. Acts upstream of or within corticospinal tract morphogenesis. Located in cytoplasm and plasma membrane. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; embryo mesenchyme; genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in Elsahy-Waters syndrome and Teebi hypertelorism syndrome 2. Orthologous to human CDH11 (cadherin 11). PHENOTYPE: Homozygous mutant animals appear healthy and fertile. [provided by MGI curators] |