| Primary Identifier | MGI:1930943 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 56437 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable GTP binding activity and calcium channel regulator activity. Predicted to be involved in negative regulation of cell growth. Located in T-tubule. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and musculature. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human RRAD (RRAD, Ras related glycolysis inhibitor and calcium channel regulator). PHENOTYPE: Mice homozygous for a knock-out allele are more susceptible to pressure overload-induced cardiac hypertrophy and display weaker left ventricular contractility than control mice at higher doses of dobutamine. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
