Primary Identifier | MGI:2685542 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 277973 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable arrestin family protein binding activity; potassium:proton antiporter activity; and sodium:proton antiporter activity. Predicted to be involved in monoatomic cation transmembrane transport and regulation of intracellular pH. Predicted to be located in several cellular components, including focal adhesion; neuron spine; and recycling endosome membrane. Predicted to be active in plasma membrane. Is expressed in brain. Human ortholog(s) of this gene implicated in end stage renal disease. Orthologous to human SLC9A5 (solute carrier family 9 member A5). PHENOTYPE: Mice homozygous for a knock-out allele exhibit enhanced learning and memory and synapse morphology. [provided by MGI curators] |