Primary Identifier | MGI:1921584 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 74334 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables beta-tubulin binding activity; guanyl-nucleotide exchange factor activity; and small GTPase binding activity. Acts upstream of or within microtubule cytoskeleton organization. Located in cytoplasm and microtubule cytoskeleton. Is expressed in several structures, including adrenal gland; genitourinary system; gut; liver; and nervous system. Orthologous to human RANBP10 (RAN binding protein 10). PHENOTYPE: Mice homozygous for a gene trap allele exhibit slight defects in erythrocyte number and volume, decreased platelet aggregattion and increased bleeding time associated with impaired platelet dense granule release. [provided by MGI curators] |