Primary Identifier | MGI:1924661 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 77411 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable mRNA binding activity. Acts upstream of or within alternative mRNA splicing, via spliceosome; morphogenesis of a branching epithelium; and positive regulation of epithelial cell proliferation. Predicted to be located in nucleus. Predicted to be part of ribonucleoprotein complex. Predicted to be active in nucleoplasm. Is expressed in several structures, including alimentary system; genitourinary system; nose; respiratory system; and skin. Orthologous to human ESRP2 (epithelial splicing regulatory protein 2). PHENOTYPE: Homozygous null mice exhibit defects in hepatic maturation, and decreased serum albumin levels and total serum protein levels. [provided by MGI curators] |