Primary Identifier | MGI:2178076 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 192654 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables acylglycerol O-acyltransferase activity; calcium-independent phospholipase A2 activity; and phospholipase A1 activity. Involved in ceramide metabolic process and glycerolipid metabolic process. Located in extracellular space and lysosome. Is expressed in several structures, including adrenal gland; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human PLA2G15 (phospholipase A2 group XV). PHENOTYPE: Homozygous mutant mice do not develop atherosclerotic lesions even when fed an atherogenic diet. [provided by MGI curators] |