Primary Identifier | MGI:109599 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 15118 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables hyaluronan synthase activity. Involved in extracellular matrix assembly; hyaluronan biosynthetic process; and polysaccharide biosynthetic process. Located in cytoplasm and nucleus. Is active in plasma membrane. Is expressed in several structures, including central nervous system; genitourinary system; jaw; sensory organ; and skin. Orthologous to human HAS3 (hyaluronan synthase 3). PHENOTYPE: Mice homozygous for a null allele are viable and fertile with normal static and dynamic compliances and display a reduced high tidal volume ventilation-induced inflammatory response. [provided by MGI curators] |