Primary Identifier | MGI:1351511 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 17463 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein homodimerization activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Part of proteasome regulatory particle. Is expressed in several structures, including brain; liver; metanephros; placenta; and spleen. Orthologous to human PSMD7 (proteasome 26S subunit, non-ATPase 7). PHENOTYPE: Homozygous mutant mice carrying a proviral insertion at this locus develop normally to the blastocyst stage but die shortly after implantation before reaching the egg cylinder stage. [provided by MGI curators] |