| Primary Identifier | MGI:2664670 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 244646 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium-activated cation channel activity; pH-gated monoatomic ion channel activity; and transmembrane transporter binding activity. Contributes to monoatomic cation channel activity and sour taste receptor activity. Involved in calcium ion transmembrane transport; cellular response to acidic pH; and detection of chemical stimulus involved in sensory perception of sour taste. Located in plasma membrane. Part of cation channel complex and receptor complex. Colocalizes with cell surface. Is expressed in circumvallate papillae; cochlea; foliate papillae; and testis. Orthologous to human PKD1L3 (polycystin 1 like 3, transient receptor potential channel interacting). PHENOTYPE: Mice homozygous for a knock-out allele are viable, fertile and grossly normal and exhibit normal taste responsiveness in various behavioral and electrophysiological tests of taste function. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
