| Primary Identifier | MGI:101919 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 11765 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including GTP-dependent protein binding activity; clathrin adaptor activity; and kinesin binding activity. Predicted to be involved in Golgi to lysosome transport; endosome to melanosome transport; and positive regulation of natural killer cell degranulation. Predicted to act upstream of or within intracellular protein transport and vesicle-mediated transport. Located in perinuclear region of cytoplasm and trans-Golgi network. Is active in presynapse. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and hemolymphoid system gland. Orthologous to human AP1G1 (adaptor related protein complex 1 subunit gamma 1). PHENOTYPE: Mice homozygous for a null allele exhibit complete embryonic lethality before implantation. Heterozygotes display slow postnatal weight gain, decreased CD4-positive, alpha beta T cell number in the thymus, and decreased body size up to 10 months of age. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
