Primary Identifier | MGI:2444928 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 244650 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable protein serine/threonine phosphatase activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in several cellular components, including mitotic spindle; photoreceptor inner segment; and photoreceptor outer segment membrane. Predicted to be active in cytoplasm. Is expressed in cerebellum; hippocampus; liver; and retina outer nuclear layer. Orthologous to human PHLPP2 (PH domain and leucine rich repeat protein phosphatase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit normal susceptibility to DSS-induced colitis. [provided by MGI curators] |