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Protein Coding Gene : Chst4 carbohydrate sulfotransferase 4

Primary Identifier  MGI:1349479 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  26887
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables N-acetylglucosamine 6-O-sulfotransferase activity. Involved in positive regulation of leukocyte tethering or rolling. Acts upstream of or within leukocyte tethering or rolling and protein sulfation. Predicted to be located in Golgi membrane. Predicted to be active in trans-Golgi network. Is expressed in several structures, including alimentary system; genitourinary system; immune system; liver; and nervous system. Orthologous to human CHST4 (carbohydrate sulfotransferase 4).
PHENOTYPE: Mice homozygous for disruptions in this gene do not accumulate lymphocytes in peripheral lymph nodes to as great an extent as normal. The animals are phenotypically normal otherwise. [provided by MGI curators]
  • synonyms:
  • Chst4,
  • GST-3,
  • HEC-GlcNAc6ST,
  • carbohydrate sulfotransferase 4,
  • high endothelial cell GlcNAC-6-sulphotransferase

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

4 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

2 Driver For