Primary Identifier | MGI:2148251 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 234733 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable RNA helicase activity and mRNA binding activity. Predicted to be involved in poly(A)+ mRNA export from nucleus. Predicted to be located in nuclear envelope. Predicted to be active in cytoplasmic stress granule and nucleus. Is expressed in cerebral cortex ventricular layer; cortical plate; orbito-sphenoid; and turbinate bone primordium. Orthologous to human DDX19B (DEAD-box helicase 19B). PHENOTYPE: Homozygous knockout is embryonic lethal. Heterozygous KO leads to increased resistance to RNA virus infection. [provided by MGI curators] |