| Primary Identifier | MGI:2442600 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 208936 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable metalloendopeptidase activity. Acts upstream of or within negative regulation of platelet aggregation. Predicted to be located in extracellular region. Predicted to be active in extracellular matrix. Is expressed in several structures, including alimentary system; brain; eye; lung; and male reproductive gland or organ. Orthologous to human ADAMTS18 (ADAM metallopeptidase with thrombospondin type 1 motif 18). PHENOTYPE: Mice homozygous for a floxed allele exhibit some fertility defects. Mice homozygous for a null allele exhibit growth and eye defects and increased susceptibility to chemically induced tumors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
