| Primary Identifier | MGI:2682328 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 234776 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription activator activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within motile cilium assembly; positive regulation of gene expression; and positive regulation of non-motile cilium assembly. Predicted to be located in nuclear body. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; heart; liver; lung; and retina. Orthologous to human ATMIN (ATM interactor). PHENOTYPE: Mice homozygous for a knock-out allele exhibit fetal lethality, craniofacial defects, midbrain exencephaly, and premature senescence of mouse embryonic fibroblasts. Homozygotes for an ENU-induced mutation exhibit left-right patterning defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
