| Primary Identifier | MGI:1915383 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 68133 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable aminomethyltransferase activity and enzyme binding activity. Predicted to be involved in glycine decarboxylation via glycine cleavage system and protein lipoylation. Located in mitochondrion. Is expressed in several structures, including alimentary system; integumental system; metanephros; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in multiple mitochondrial dysfunctions syndrome. Orthologous to human GCSH (glycine cleavage system protein H). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size and fail to develop beyond early post-implantation stages with no recognizable embryonic features such as somites or cranial neural folds. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
