Primary Identifier | MGI:1928485 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 56690 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables malonyl-CoA decarboxylase activity. Involved in malonyl-CoA catabolic process and positive regulation of fatty acid oxidation. Located in mitochondrial matrix. Is expressed in several structures, including alimentary system; nervous system; nose; respiratory system; and urinary system. Human ortholog(s) of this gene implicated in cardiomyopathy. Orthologous to human MLYCD (malonyl-CoA decarboxylase). PHENOTYPE: Mice homozygous for a null allele exhibit altered cardiac metabolism following ischemia and improved recovery. [provided by MGI curators] |