Primary Identifier | MGI:1915116 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 67866 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable serine-type endopeptidase inhibitor activity. Acts upstream of or within negative regulation of inflammatory response and negative regulation of wound healing. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in eye; male reproductive gland or organ; midbrain; and parathyroid gland. Orthologous to human WFDC1 (WAP four-disulfide core domain 1). PHENOTYPE: Homozygous mice for a null allele exhibit decreased susceptibility to influenza A virus infection and enhanced wound healing. [provided by MGI curators] |