| Primary Identifier | MGI:1916040 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 68790 |
| Mgi Type | lncRNA gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables core promoter sequence-specific DNA binding activity. Involved in in utero embryonic development and lung development. Acts upstream of or within several processes, including chromatin organization; embryonic lung development; and lateral mesoderm development. Predicted to be located in nucleus. Is expressed in brain; gut; heart; liver; and lung. Orthologous to human FENDRR (FOXF1 adjacent non-coding developmental regulatory RNA). PHENOTYPE: Homozygotes for a null allele die neonatally with respiratory failure and lung, gastrointestinal tract and heart defects. Homozygotes for another null allele show altered lung lobe development. Chimeric null embryos die during organogenesis with omphalocele and ventricle myocardium hypoplasia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
