| Primary Identifier | MGI:1347469 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 14241 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity. Acts upstream of or within several processes, including Peyer's patch morphogenesis; proteoglycan biosynthetic process; and visceral mesoderm-endoderm interaction involved in midgut development. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; heart; sensory organ; and urinary system. Human ortholog(s) of this gene implicated in otosclerosis 11. Orthologous to human FOXL1 (forkhead box L1). PHENOTYPE: Mice homozygous for disruptions in this gene exhibit impaired stomach and intestine development, including impaired parietal cell differentiation, abnormal intestinal epithelium and crypt structure, gastric mucosal hyperplasia, growth retardation, and sometimes postnatal lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
