| Primary Identifier | MGI:1914693 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 67443 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including microtubule binding activity; phosphatidylethanolamine binding activity; and ubiquitin protein ligase binding activity. Involved in autophagy. Acts upstream of or within positive regulation of mucus secretion. Located in axoneme; membrane; and vacuole. Is expressed in several structures, including central nervous system; heart; limb; peripheral nervous system ganglion; and sensory organ. Orthologous to several human genes including MAP1LC3B2 (microtubule associated protein 1 light chain 3 beta 2). PHENOTYPE: Mice homozygous for a knock-out allele develop, breed and behave normally and display a normal life span. In culture, mutant MEFs maintain wild-type levels of fibronectin (FN) protein despite reduced FN synthesis, and show normal induction of autophagosomes under starvation conditions. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
