Primary Identifier | MGI:2446486 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 234836 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables cytokine activity. Acts upstream of or within neutrophil differentiation and positive regulation of cytokine production involved in inflammatory response. Located in extracellular space. Orthologous to human IL17C (interleukin 17C). PHENOTYPE: Mice homozygous for a reporter allele exhibit decreased susceptibility to experimental autoimmune encephalomyelitis. Mice homozygous for a knock-out allele exhibit increased susceptibility to induced psoriasis. [provided by MGI curators] |