| Primary Identifier | MGI:1925559 | Organism | mouse, laboratory |
| Chromosome | 17 | NCBI Gene Number | 78309 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 9.1.0) Predicted to enable ubiquitin protein ligase binding activity and zinc ion binding activity. Predicted to be involved in microtubule cytoskeleton organization; protein ubiquitination; and regulation of mitotic nuclear division. Predicted to be located in cytosol. Predicted to be part of cullin-RING ubiquitin ligase complex. Is expressed in brain; hemolymphoid system gland; muscle tissue; retina nuclear layer; and testis. Orthologous to human CUL9 (cullin 9). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased body weight, increased incidence of tumors, and decreased cellular sensitivity to radiation-induced apoptosis. [provided by MGI curators] |