| Primary Identifier | MGI:894694 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 108148 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable manganese ion binding activity and polypeptide N-acetylgalactosaminyltransferase activity. Predicted to be involved in protein O-linked glycosylation via serine; protein O-linked glycosylation via threonine; and protein maturation. Predicted to be located in Golgi stack and perinuclear region of cytoplasm. Predicted to be active in Golgi apparatus. Is expressed in several structures, including alimentary system; floor plate; lens; lung mesenchyme; and submandibular gland primordium. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type II. Orthologous to human GALNT2 (polypeptide N-acetylgalactosaminyltransferase 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased circulating HDL cholesterol levels under both chow- and Western diet-fed conditions, a marked elevation in fasting triglyceride levels, and delayed postprandial triglyceride clearance. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
