Primary Identifier | MGI:3045323 | Organism | mouse, laboratory |
Chromosome | 8 | NCBI Gene Number | 330863 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable zinc ion binding activity. Acts upstream of or within negative regulation of Ras protein signal transduction; positive regulation of neuron projection development; and positive regulation of ubiquitin-dependent protein catabolic process. Located in cytoplasm. Is expressed in brain; dorsal root ganglion; and spinal cord. Orthologous to human TRIM67 (tripartite motif containing 67). PHENOTYPE: Mice homozygous for a null allele display decreased brain size with forebrain abnormalities, impaired spatial learning, decreased response to social novelty, impaired coordiation and reduced grip strength. [provided by MGI curators] |