| Primary Identifier | MGI:2443921 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 270110 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable transcription corepressor activity. Predicted to be involved in immature B cell differentiation and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including brain; diaphragm; liver; lung; and musculature. Human ortholog(s) of this gene implicated in common variable immunodeficiency 14. Orthologous to human IRF2BP2 (interferon regulatory factor 2 binding protein 2). PHENOTYPE: Homozygous mice are rarely born alive and those that are do not survive past 4 weeks of age. Fetal liver erythropoiesis is abnormal in these mice. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
