| Primary Identifier | MGI:2135608 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 93742 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable identical protein binding activity; phosphatidylinositol phosphate binding activity; and protein phosphatase binding activity. Involved in several processes, including negative regulation of peptidyl-threonine phosphorylation; positive regulation of myelination; and positive regulation of receptor internalization. Acts upstream of or within several processes, including apical constriction; centrosome localization; and wound healing, spreading of cells. Located in several cellular components, including Schmidt-Lanterman incisure; internode region of axon; and lateral loop. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ. Orthologous to human PARD3 (par-3 family cell polarity regulator). PHENOTYPE: Mice homozygous for a null allele exhibit embryonic lethality at E12.5 associated with growth retardation, abnormal heart development, and abnormal epicardial cell development. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
