Primary Identifier | MGI:1919035 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 71785 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable platelet-derived growth factor receptor binding activity. Acts upstream of or within cellular response to amino acid stimulus and regulation of peptidyl-tyrosine phosphorylation. Located in extracellular space. Is expressed in bladder; brain; and urethra of male. Human ortholog(s) of this gene implicated in prostatic hypertrophy. Orthologous to human PDGFD (platelet derived growth factor D). PHENOTYPE: Mice homozygous for a knock-out allele show a mild vascular phenotype characterized by abnormal pericyte morphology within cardiac tissue, slightly increased systolic and diastolic blood pressure, and altered serum levels of calcium and chloride ions. [provided by MGI curators] |