| Primary Identifier | MGI:1918794 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 71544 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables GTPase activator activity. Acts upstream of or within negative regulation of Rho protein signal transduction; negative regulation of systemic arterial blood pressure; and negative regulation of vascular associated smooth muscle contraction. Predicted to be located in cytoplasm. Orthologous to human ARHGAP42 (Rho GTPase activating protein 42). PHENOTYPE: Mice homozygous for a hypomorphic allele exhibit hypertension and increased vascular smooth muscle contractility. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
