| Primary Identifier | MGI:1920076 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 72826 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Involved in negative regulation of macrophage activation. Predicted to be active in nuclear speck. Is expressed in esophagus and heart ventricle. Orthologous to human FAM76B (family with sequence similarity 76 member B). PHENOTYPE: Mice homozygous for a knock-out allele have enlarged spleens with altered cell populations and white pulp hypertrophy and show increased microglial cell activation and neuroinflammation with further enhancement of the inflammatory response after brain injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
