Primary Identifier | MGI:95594 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 14345 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables alpha-(1->3)-fucosyltransferase activity. Involved in lymphocyte migration into lymph node; positive regulation of leukocyte tethering or rolling; and positive regulation of neutrophil migration. Located in cell periphery and cell surface. Is expressed in several structures, including central nervous system; ear; extraembryonic component; genitourinary system; and respiratory system. Orthologous to human FUT4 (fucosyltransferase 4). PHENOTYPE: Mice homozygous for a knock-out allele show a modest increase in blood neutrophils, monocytes and eosinophils, and increased leukocyte rolling velocities. [provided by MGI curators] |