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Protein Coding Gene : Mtnr1b melatonin receptor 1B

Primary Identifier  MGI:2181726 Organism  mouse, laboratory
Chromosome  9 NCBI Gene Number  244701
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable melatonin receptor activity. Predicted to be involved in several processes, including negative regulation of cell communication; positive regulation of circadian sleep/wake cycle, non-REM sleep; and regulation of transmission of nerve impulse. Predicted to act upstream of or within circadian rhythm. Predicted to be active in plasma membrane. Is expressed in alimentary system; central nervous system; eye; and reproductive system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MTNR1B (melatonin receptor 1B).
PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile and display no obvious circadian phenotype. [provided by MGI curators]
  • synonyms:
  • Mt2,
  • melatonin receptor 1B,
  • Mtnr1b,
  • Mel1b

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

6 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For