Primary Identifier | MGI:2181726 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 244701 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable melatonin receptor activity. Predicted to be involved in several processes, including negative regulation of cell communication; positive regulation of circadian sleep/wake cycle, non-REM sleep; and regulation of transmission of nerve impulse. Predicted to act upstream of or within circadian rhythm. Predicted to be active in plasma membrane. Is expressed in alimentary system; central nervous system; eye; and reproductive system. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human MTNR1B (melatonin receptor 1B). PHENOTYPE: Mice homozygous for a knock-out allele are viable and fertile and display no obvious circadian phenotype. [provided by MGI curators] |